Reference Ranges
Evidence-based target ranges for hormone therapy monitoring
Select Profile
Target ranges for feminizing hormone therapy per Endocrine Society guidelines
Transfeminine (MTF HRT) Reference Ranges
Hormones
| Test | Range | Unit | Notes |
|---|---|---|---|
| Estradiol (E2) | 367 - 734 | pmol/l | ~100-200 pg/mL |
| Testosterone (T) | < 1.7 | nmol/l | Suppression target |
| Free Testosterone | < 0.05 | nmol/l | Suppression target |
| FSH | < 5 | U/l | Suppression target |
| LH | < 5 | U/l | Suppression target |
| Progesterone | 0 - 5 | nmol/l | |
| Prolactin | 86 - 500 | mIU/l | |
| SHBG | 30 - 100 | nmol/l | |
| Free Androgen Index | < 5 | — | Suppression target |
| TSH | 0.4 - 4 | mIU/L |
Liver Function
| Test | Range | Unit | Notes |
|---|---|---|---|
| Albumin | 35.1 - 50 | g/l |
Blood Count
| Test | Range | Unit | Notes |
|---|---|---|---|
| Hemoglobin | 12 - 16 | g/dL | |
| Hematocrit | 36 - 46 | % |
Vitamins & Minerals
| Test | Range | Unit | Notes |
|---|---|---|---|
| Potassium | 3.5 - 5 | mEq/L |
Note on suppression targets
Tests marked with "<" indicate suppression is desired. Values below the threshold are considered optimal, and there is no lower bound flagged as abnormal.
Unit Conversions
Different labs use different units. Here are common conversions:
Estradiol
Testosterone
Sources & References
The reference ranges used in this application are based on the following clinical guidelines and resources:
Endocrine Society Clinical Practice Guideline
Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons (2017)
Primary source for transfeminine and transmasculine target hormone ranges. Recommends maintaining estradiol at 100-200 pg/mL and testosterone <50 ng/dL for transfeminine individuals.
WPATH Standards of Care (SOC-8)
World Professional Association for Transgender Health Standards of Care, Version 8 (2022)
Comprehensive guidelines covering all aspects of transgender healthcare including hormone therapy monitoring.
NHS Gender Dysphoria Guidelines
NHS England service specification for gender identity services
UK-specific guidance for hormone therapy in gender-affirming care.
Randox Health Reference Ranges
Laboratory reference intervals used by Randox Health for hormone panels
Source for default cisgender reference ranges. Uses pmol/L for estradiol and nmol/L for testosterone (SI units common in UK labs).
British Menopause Society Tools
Hormone level interpretation guidance
Additional context for interpreting hormone levels in various clinical scenarios.
Medical Disclaimer
These reference ranges are provided for informational purposes only and should not replace professional medical advice. Always consult with your healthcare provider to interpret your results and determine appropriate target ranges for your individual care plan.